DISC1 and schizophrenia: Previous studies reported left side-specific pallidal predisposing abnormalities in schizophrenia, such as an association between left pallidal volume and Disrupted in schizophrenia 1 (DISC1) single-nucleotide polymorphism (SNP) rs1685475653, and a higher-than-normal blood flow in the left globus pallidus in never-medicated patients with schizophrenia54.