Chromosomal translocation is observed particularly in alveolar rhabdomyosarcoma, including two patterns of translocations: t(2;13)(q35;q14) with the PAX3-FOXO1 fusion gene, and t(1;13)(p36;q14) with the PAX7-FOXO1 fusion gene. The gene discussed is FOXO1; the disease is alveolar rhabdomyosarcoma.