TGFB1 and hepatocellular carcinoma: TGF-β1 was one of the 841 putative miRNA sites that were predicted to binding miR-663a by miRWalk, TargetScan, PITA, DIANAmT, and miRanda programs (Fig. 4a and Additional file 1) and related to the role in HCC metastasis according to the relevant reports [25, 26].