De Strooper et al. [15] evaluated that FAM19A4 methylation was detected in all cervical cancer and CINII/III lesions with HPV infection lasting ≥5 years (advanced CINII/III), but only 82.8% of cervical cancer and 86.4% of advanced CINII/III were detected by cytological tests, revealing FAM19A4 methylation could predict those patients with high risk of progression to cervical cancer and its precancerous lesion. This evidence concerns the gene TAFA4 and cervical cancer.