It is typically upregulated in lipopolysaccharide-stimulated monocytes and macrophages [20, 21] .In recent years, some studies have revealed that FAM19A4 methylation has a close relationship with cervical cancer and is a putative cervical cancer biomarker and an effective triage method for hrHPV-positive women in cervical screening [7, 14, 15, 22–24]. This evidence concerns the gene TAFA4 and cervical cancer.