However, another group found an increased relapse rate in women treated with both GnRH agonists and GnRH antagonists, and suggested that relapses could be due to either to cessation of immune therapy, or to stress, which has been suggested to trigger relapses of MS, as well as to the possible effects of the hormones used in ART [131,132]. Here, GNRH1 is linked to myeloid sarcoma.