In addition, in this study, 10 of 2193 (0.5%) pregnant women delivered newborns with congenital CMV infection, and 3 of 10 infants with congenital CMV infection were delivered to pregnant women who had primary CMV infection during pregnancy, defined as a CMV IgG avidity index of < 35%, CMV IgM >1.2 index, or detection of CMV IgG seroconversion. Here, CD40LG is linked to cytomegalovirus infection.