In a 5.3-year cohort study, Yang et al. [23] also identified HPT as a novel biomarker that complements urine albumin in predicting chronic renal insufficiency (< 60 mL/min per 1.73 m2) in T2D patients with eGFR > 80 mL/min per 1.73 m2. This evidence concerns the gene ALB and type 2 diabetes mellitus.