Recombinant, purified FUS, disease-related mutant FUS, and other ALS/FTD-related hnRNPs harboring a PY-NLS formed fibrils, but no droplets, while fibrillization was inhibited by equimolar amounts of recombinant transportin-1 [48,49,50,51]. This evidence concerns the gene TNPO1 and frontotemporal dementia.