The associated quantitative results are shown in Figure 2K,L and Figures S2F and S3B. Taken together, these results indicated that genetic alteration of FOXM1c expression strongly affected the invasion and migration of oesophageal cancer cells; thus, FOXM1c may play a critical role in oesophageal cancer metastasis. This evidence concerns the gene FOXM1 and carcinoma of esophagus.