FOXM1 and carcinoma of esophagus: FOXM1a function has been poorly characterized due to its extremely low expression, FOXM1b and FXOM1c mainly regulate oncogene transcription in the nucleus, and FOXM1d promotes cancer EMT and progression via interactions with ROCKs in the cytoplasm.13, 14 Although FOXM1b, FOXM1c and FOXM1d were investigated in certain cancer types,14, 35, 41 the distribution and function of these isoforms in oesophageal cancer remain unknown.