KLF2 and lung cancer: 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81 Particularly, long non‐coding RNA XIST acts as an oncogene in non–small‐cell lung cancer by epigenetically repressing KLF2 expression, indicating that lncRNAs also exert mediating function by targeting KLF protein.75 Our further study may focus the regulatory axis of lncRNA‐miRNA in the progression of lung cancer, as well as to elucidate the possible mechanisms.