FCGR3B and systemic lupus erythematosus: In an independent CNV assay, we showed that deletion in the FCGR3B gene is associated with increased susceptibility to SLE (p = 1.66 x 10−3, OR = 3.6 [95% CI, 1.7–8.3]), while duplication in this gene is a protective factor for the development of SLE (p = 1.55 x 10−4, OR = 0.2 [95% CI, 0.1–0.4]) (S4 Fig).