ADAM3A and systemic lupus erythematosus: In the CNVRs analysis performed from the Cytoscan HD array data (23 SLE and 110 controls), a deletion (CN < 2) partially encompassing the ADAM5 gene and entirely overlapping the ADAM3A gene was identified as a potential candidate for increased susceptibility to SLE (p = 0.0352; OR = 3.3 [95% CI, 1.0–14.1]) (S3 Fig and S3 Table).