MAK and retinal degeneration: Only a few cases of human retinal degeneration have been reported to be caused by inserted retrotransposons; an Alu insertion on exon 9 of MAK, and intronic Alu insertion in OPA1 (Bujakowska, White, Place, Consugar, & Comander, 2015; Gallus et al., 2010; Tucker et al., 2011).