TLR4 and kidney disorder: Myo1e also binds phospholipids with high affinity55 and regulates podocyte function and glomerular filtration.56 Furthermore, the ERK‐mediated translocation of Myo1e from the cytosol to the tips of lamellipodia is essential for cell motility and migration 57 and Myo1e regulates TLR4‐triggered macrophage spreading and chemokine release as part of the innate immune response.58 Myo1e has therefore been linked to a number of diseases such as atherosclerosis,59 coronary artery disease and kidney disease.60