OGT and neoplasm: It has been observed that elevated levels of O‐GlcNAcylation in CRC cells prompted us to investigate whether O‐GlcNAcylation has a tumour‐promoting function.27 We found that knockdown of OGT resulted in a significant decrease in DDX5 and O‐GlcNAcylation levels (Figure 2A) in SW480 cells, as well as the abilities of cell proliferation (Figure 2B), colony formation (Figure 2D), and migration (Figure 2E).