Their results revealed that upregulation of Lcn2 not only significantly stimulated the secretion of HGF, IGF‐1, FGF and VEGF in MSCs but also ameliorated renal dysfunction caused by cisplatin‐induced AKI.79 Lastly, the article by Hagiwara et  al suggested kallikrein‐modified MSCs were also able to secrete recombinant human kallikrein with elevated VEGF levels in culture medium.58 The gene discussed is IGF1; the disease is acute kidney injury.