In another study, Zhang et al. successfully constructed 68Ga-BBN (Bombesin)-RGD, a heterodimeric PET tracer targeting both GRPR (gastrin-releasing peptide receptor) and integrin αvβ3, and the clinical data indicated the safety and efficiency of dual-targeting PET radiotracer in prostate cancer diagnosis and staging [44]. This evidence concerns the gene GRP and prostate carcinoma.