CACNA2D1 and early repolarization associated with ventricular fibrillation: Burashnikov et al. [83] reported CACNA2D1 may be a BrS susceptibility gene on the basis of the fact that three different missense mutations (S709N, D550Y and Q917H) were identified in CACNA2D1 in three BrS patients out of 205 patients with BrS, short QT, idiopathic ventricular fibrillation and early repolarization syndrome (ERS).