CCL20 and breast cancer: In the MDA-MB-231 breast cancer model (69), expression of CCL20 and TAM accumulation in xenografted tumors are suppressed by knock down of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain-2 (CITED2), a transcriptional co-regulator whose expression is increased in human invasive ductal carcinoma compared to normal mammary tissues and further enhanced in metastatic breast cancer (71, 72).