CD8A and parasitic infectious disease: In this experimental setting, both CD8+ T cell populations that can be tracked according to their different congenic markers (both T cell populations: CD45.2+; WT OT-1: CD90.1+; HVEM−/− OT-1: CD90.1−; recipient: CD45.1+CD45.2−) are exposed to the same inflammatory environment and parasitemia level, thus specifically allowing the analysis of the HVEM function.