Using our protocol, severe cerebral symptoms in the PbA infection model occurred at day 6 p.i. with most of the mice succumbing to cerebral pathology between day 6 and 8 p.i. CD160 expression on CD8+ T cells was thus analyzed early after infection (d 3 p.i,), before first symptoms occurred (d 5 p.i.), upon onset of severe symptoms (d 6 p.i.)and at the peak of T cell activation (d 7 p.i.). Here, CD160 is linked to infection.