ITGAX and drug-induced lupus erythematosus: Mice with a Blimp-1ko phenotype in all CD11c-expressing cells including DCs (Blimp-1flox/flox; CD11c-CRE+) present an increased secretion of interleukin 6, an increased differentiation of effector T cells and suffer from the development of a lupus-like syndrome (71).