IFNA1 and infection: In vivo cytokine profile analysis during the 1st week of infection shows a systemic decrease of pro-inflammatory cytokines (IL-1β, IL-6, and TNFα), while an increase of the anti-inflammatory cytokine IL-10 and IFNα is detected (Nfon et al., 2010; Diaz-San Segundo et al., 2012, 2013; Perez-Martin et al., 2012; Sei et al., 2016).