Out of all drugs, 36 (38%) were used for treatment of patients with oncologic diseases (e.g., relapsed or refractory CD30+ Hodgkin lymphoma), 22 (23%) for metabolic diseases (e.g., type 1 Gaucher disease), and 37 (39%) for other diseases (e.g., cystic fibrosis, severe hepatic veno-occlusive disease). Here, TNFRSF8 is linked to metabolic disease.