Third, we tested whether β‐RA may increase the survival in two models of neuroinflammation and early death due to mitochondrial Complex I deficiency, i.e., the zebrafish embryos treated with MPTP, which mimics Parkinson disease (Diaz‐Casado et al, 2018); and the Ndufs4 knockout mouse model, which mimics Leigh syndrome (Quintana et al, 2010). This evidence concerns the gene NDUFS4 and Leigh syndrome.