TP53 and cancer: As hepatic cell line QSG-7701 and cancer cell line LM3 are p53 wild-type, we examined the cellular functions and mechanisms in other p53 wild-type hepatic cell line L02 and cancer cell line SMMC-7721, p53 mutant-type cancer cell line Huh7 and p53-deficient HCC cell line Hep3B [24].