CEBPB and breast carcinoma: The amount of LIP induced upon doxorubicin treatment was inversely correlated with the lysosome (Fig. 1e) and proteasome (Fig. 1f) activity in the cell lines examined, suggesting that – as observed for other solid tumors [5, 27] – the degradation via lysosome and proteasome is critical in preserving C/EBP-β LIP level in breast cancer.