It is important to note that among the coinfected patients, the four who developed KS also had intermediate expression MBL haplotypes, three with HYA/LXA and one with LYA/LYO, suggesting that these haplotypes may interfere with the clinic development of SK in HIV/HHV-8 coinfected patients. The gene discussed is MBL2; the disease is Kaposi's sarcoma.