CD4 and neoplasm: Despite a slight increase in the expression of the CD69 and CD25 activation markers on tumor stimulated AbTCR-T cells compared to CAR-T cells (Fig. 3a), AbTCR+ CD4+ cells expressed substantially lower levels of the PD-1 exhaustion marker than CAR+ CD4+ cells, and, in both CD4+ and CD8+ AbTCR-T cells, LAG-3 was significantly lower (Fig. 3e).