Interestingly, while adipose (pI.3), skin/adipose (pI.4), endothelial (pI.7) and ovary (pII) were shown to be activated during cancer progression [36, 55, 63], another report demonstrated that the transcripts associated with pI.1 and pII were shown to best correlate with aromatase protein expression [50]. This evidence concerns the gene CYP19A1 and cancer.