CD4 and Miyoshi myopathy: Similar with PB, the frequency of BM aTregs among CD4+ T cells was dramatically higher in MGUS (5.52% ± 1.45%, n = 20, P < 0.0001) and MM patients (6.24% ± 1.51%, n = 26, P < 0.0001) than healthy adults (3.34% ± 1.23%, n = 18), whereas there was no difference between MGUS and MM group (P = 0.11) (Fig. 2a).