CD4 and Miyoshi myopathy: Quantification analysis showed that PB aTregs among CD4+ T cells were notably elevated in MGUS (5.70 ± 1.50%, n = 10, P < 0.01) and MM patients (6.52% ± 1.37%, n = 16, P < 0.0001) compared with healthy adults (4.13% ± 0.84%, n = 10), while there was no difference between MGUS and MM group (P = 0.16) (Fig. 1a).