KLF8 and hepatocellular carcinoma: KLF8 mRNA levels were higher in pcDNA3.1-KLF8-transfected HCC cells than in pcDNA3.1-transfected HCC cells; the relative KLF8 mRNA level was 472.66 ± 8.65 (P < 0.001, n = 3) (Fig. 2a).