The coordinated action of CCL2 and interleukin-6 (IL-6)14 also nurtured the supply of monocyte-derived macrophages to the vascular wall in apolipoprotein E deficient mice (ApoE−/−) exposed to continuous infusion of angiotensin II (Ang II), a prototypical AAA model15. The gene discussed is APOE; the disease is triple-A syndrome.