However, blocking autocrine VEGF by anti-human VEGF neutralization antibody (NAb) did not have an appreciable effect on the tube formation of EBV-infected NPC cells; in contrast, a strong inhibition of the tube formation of human umbilical vein endothelial cells (HUVECs) was observed following VEGF NAb treatment (Supplementary Fig. 7b). This evidence concerns the gene VEGFA and nasopharyngeal carcinoma.