Using 10 EBV-positive and 7 EBV-negative NPC biopsies (see Methods for detailed sample information), we showed that some DEGs in Fig. 3d, including F3, CYR61, EphA2, and TNFRSF12A, were indeed upregulated in EBV-positive NPC samples (Fig. 3f). The gene discussed is CCN1; the disease is nasopharyngeal carcinoma.