In our previous gene expression meta-analysis, we identified 168 significant pathways in the brain PFC region7, and 60.1% of these (101 out of 168) were identified in either blood AD or blood MCI, including PNOROS (BH.pval = 1.26E-12, ratio = 44/180), NFkB Signalling (BH.pval = 1.26E-11, ratio = 41/173), iNOS Signalling (BH.pval = 5.37E-7,ratio = 15/44), Mitochondrial Dysfunction (BH.pval = 2.24E-06, ratio = 37/172), and Oxidative Phosphorylation (BH.pval = 4.27E-4, ratio = 24/110). Here, NFKB1 is linked to Alzheimer disease.