TCIRG1 and Alzheimer disease: Although DEGs identified in the discovery dataset had an enrichment of DEGs identified in GSE6613 (OR = 2.37, 95%CI 1.91–2.95, pval = 8.35E-15; and OR = 2.78, 95%CI 2.24–3.46, pval = 2.74E-21, for AD and MCI respectively), only three of the top DEGs listed in Table 1 were re-discovered in GSE6613, namely WDFY3, TCIRG1, and NEMF/SDCCAG1.