SOAT1 and Alzheimer disease: For the up-regulated AD-DEGs in blood, 119 significant canonical pathways were identified, including iNOS Signalling (BH.pval = 9.77E-7, ratio = 21/43); B-Cell Receptor Signalling (BH.pval = 3.55E-6, ratio = 48/178); JAK/Stat Signalling (BH.pval = 3.55E-6, ratio = 29/83); and Production of Nitric Oxide and Reactive Oxygen Species in Macrophages (PNOROS, BH.pval = 3.55E-6, ratio = 50/192).