Ginsenoside Rg3 is one of the active ingredients of ginseng, and it can suppress tumor angiogenesis by impairing the biological activity of endothelial progenitor cells and attenuating VEGF-dependent p38/ERK signaling and Akt/endothelial nitric oxide synthase signaling in vitro16,17. The gene discussed is VEGFA; the disease is neoplasm.