Of note, previous studies have shown that EBV-miR-BART1 activates PI3K-AKT, FAK-p130Cas and MAPK-ERK1/2 pathways, miR-BART10-3p activates β-catenin/Snail signaling and miR-BART7 activates PI3K/AKT and p-GSK-3β-ser9 signaling to promote NPC metastasis [14–16]. Here, PTK2 is linked to nasopharyngeal carcinoma.