Since p21 is a key regulator of the cell cycle and associated with G1/G2 arrest [21] and BAK serves a pro-apoptotic function [22], rendering both as modulators of cell survival and proliferation, we thus assessed the effect of TRPM7 on the viability and proliferation of lung cancer cells using the SRB cell viability assay. The gene discussed is TRPM7; the disease is lung cancer.