Furthermore, TRPM7-specific survival analysis of our lung cancer cohort showed that patients with high expression of TRPM7 exhibited worse cumulative survival than those with low TRPM7 expression (p < 0.001), with a 46.0 and 59.1% difference in survival at third and fifth year, respectively (Fig. 2b and Additional file 1: Figure S1). The gene discussed is TRPM7; the disease is lung carcinoma.