While no data has been reported so far in the case of ovarian cancer, the evidence of major dysfunction in TIDCs and the known ability of factors present in the ovarian TME (such as VEGF) to systemically inhibit DC generation from hematopoetic cell precursors [95] suggests that impairments similar to those found in other cancer types should also be present in ovarian cancer patients. Here, VEGFA is linked to ovarian cancer.