Furthermore, a recent study, which applied early medical nutrition therapy (MNT) and lifestyle intervention from the 13th to the 24th–28th gestational week in high risk pregnant individuals (BMI > 30 kg/m2 and/or prior GDM in history) found that only non-carriers of the MTNR1B rs10830963 risk allele G benefited from the 3 months intervention as measured by the incidence of GDM diagnosed at routine OGTT [24]. Here, MTNR1B is linked to gestational diabetes.