This high prevalence of remaining overweight/obese, together with the strong correlations found in our study between C-peptide/proinsulin and cardiovascular risk markers like body composition, lipids, and blood pressure, indicates that the GDM diagnosis overlaps with the metabolic syndrome to a great extent [30] and is potentially linked to the insulin-like growth factor (IGF) system [31]. This evidence concerns the gene IGF1 and metabolic syndrome.