At 24 hours after infection, serum levels of Il-6, IL-17, IL-10, TNFα and IL1β were unchanged and while the levels of Il-6, IL-10, TNFα and IL1β increased in Ddx3xfl/y Vav-iCre relative to control animals at 72h, the difference only reached significance in the case of IL-10. The gene discussed is TNF; the disease is infection.