These data, coupled with our new observations of ventricular dilation in adult kif6 mutants (Fig 5), suggest that Kif6 is required for the post-embryonic, robust development of the EC cilia within the ventricles of the brain as was reported in other zebrafish mutants displaying similar late-onset scoliosis, as observed in kif6 mutant zebrafish [19, 26]. The gene discussed is KIF6; the disease is scoliosis.