Histopathologic analysis showed that approximately 80% of the tumor burden in KrasLSL-G12D/+; Nkx2-1F/F; Foxa1F/F; Foxa2F/F mice consisted of mucinous HNF4α-positive adenocarcinomas (Figure 2—figure supplement 1A). The gene discussed is HNF4A; the disease is neoplasm.