BRCA1 and colorectal cancer: For example, in colorectal cancer, Wang et al. (2017) found that aberrant expression of two miRNAs (hsa-mir-25 and hsa-mir-31), one TF (BRCA1), and two other genes (ADAMTSL3 and AXIN1) affected patient survival, and thus provided clues regarding the components that determine colorectal cancer prognosis.