We previously performed a deep pathological phenotyping of a large cohort of PD patients (n=140), who died with or without dementia and included systematic evaluation of SYN, Tau NFTS, Aβ plaque, TDP-43, CVD and HpScl, as well as genotyping for Apolipoprotein E (APOE) and MAPT tau haplotype [23]. Here, TARDBP is linked to Parkinson disease.