GBA1 and Gaucher disease: Observations of PD-like clinical symptoms and SYN pathology in adult patients with the multisystem lysosomal storage disease Gaucher’s disease with homozygous mutations in the Glucocerebrosidase A1 (GBA1) gene, led to the discovery of increased frequency of heterozygous GBA1 mutation carriers in LBD patients compared to the general population [50].