Further, determinants such as CLND3, TESC, which were high-risk indicators in LUAD, were detected as positive prognostic factors in unselected NSCLC (Figure 5A, Supplementary Table 1), and determinants such as ATP1B3, HPCAL3, COL4A6, SLUG, PARD6G, SOX2, CLCA2, STF1, SKP2, which were positive indicators in LUAD, were detected as negative prognostic factors in unselected NSCLC (Figure 5A, Supplementary Table 1). The gene discussed is COL4A6; the disease is non-small cell lung carcinoma.