Further, determinants such as CLND3, TESC, which were high-risk indicators in LUAD, were detected as positive prognostic factors in unselected NSCLC (Figure 5A, Supplementary Table 1), and determinants such as ATP1B3, HPCAL3, COL4A6, SLUG, PARD6G, SOX2, CLCA2, STF1, SKP2, which were positive indicators in LUAD, were detected as negative prognostic factors in unselected NSCLC (Figure 5A, Supplementary Table 1). This evidence concerns the gene SOX2 and non-small cell lung carcinoma.