Infection with T. suis also increased mucosal barrier function-related gene expression with fold changes > 12 for RETNLB (p < 0.005), compared to the control group, and up-regulation of other helminth infection-related genes, such as the mucin MUC5AC (p < 0.01), Th2 cytokine IL13 (p < 0.005), and goblet cell trefoil factors TFF2 (p < 0.01), TFF3 (p < 0.005), indicating activation of local Th2 mucosal responses. The gene discussed is TFF2; the disease is helminthiasis.