CAV3 and heart failure: Multiple murine models of heart failure such as pressure overload induced by transverse aortic constriction (TAC) (Feiner et al., 2011), transgenic mice with constitutive overexpression of A1-adenosine receptor and angiotensin-II infusion (Markandeya et al., 2015), report that there is significant loss of Cav3 and caveolae at the sarcolemma in ventricular myocytes.