The eosinophil major basic protein (MBP), a constituent of the eosinophil secondary granule, is implicated in cytotoxicity and mediation of allergic disorders such as asthma and the level of eosinophil MBP was reported to be high in biological fluids from patients with asthma and other eosinophil-associated disorders [12]. This evidence concerns the gene PRG2 and asthma.