ITGB3 and autoimmune polyendocrinopathy: In clots generated from plasma of both APS and VTE patients the proteins involved in platelet adhesion, activation, and aggregation, like fermitin family homolog 3, multimerin-1, TREM-like transcript-1, integrin alpha-IIb (GPIIb), integrin beta-1 (GPI), integrin beta-3 (GPIII), integrin-linked protein kinase, talin-1, vinculin, filamin A, platelet glycoprotein IX (GPIX), platelet glycoprotein Ib alpha and beta chain (GPIbA, GPIbB), and TSP1 were overrepresented as compared to healthy controls (Fig. 2D, Supplemental Table 1).