ITGAX and parasitic infectious disease: Consistently, serum levels of IFN-α and IFN-β in Traf3f/f CD11c-cre mice were much higher than in WT and Traf3f/wt CD11c-cre mice 24 h after YM infection (Fig. 6f), leading to significantly reduce parasitemia and host mortality (Fig. 6g, h).